Diseases and Conditions

Undifferentiated pleomorphic sarcoma

Risk factors

Factors that may increase the risk of undifferentiated pleomorphic sarcoma include:

  • Older age. This cancer tends to occur in adults older than 50, though it can occur at any age.
  • Previous radiation therapy. Rarely, this cancer can develop in an area of the body that was previously treated with radiation therapy.

Most people who develop undifferentiated pleomorphic sarcoma have no known risk factors, and many people who have risk factors never develop the cancer.